Beilstein J. Org. Chem.2013,9, 173–179, doi:10.3762/bjoc.9.20
-(ethylsulfonyl)-2-methoxy-1,3-dinitrobenzene (4a) have been precisely physicochemically characterised.
Keywords: angiogenesis; pharmacophoric ligand; synthesis of 5-(ethylsulfonyl)-2-methoxyaniline; VEGFR2tyrosinekinaseinhibitors; Introduction
5-(Ethylsulfonyl)-2-methoxyaniline (5) is a starting material
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Graphical Abstract
Figure 1:
The AAZ ligand conformer from PDB complex 1Y6A and its VEGFR2 intermolecular interaction map depict...